Antibody affinity chromatography

Antibody-based products are a major source of new therapies. Affinity chromatography plays a major role in their production.

Protein A is the most widely used affinity purification step today and the industrial standard for capturing monoclonal antibodies. Protein A media combine high selectivity with high purity in one single step. They permit a generic approach that simplifies process development and supports purification platform development.

The MabSelect™ family is the flagship of GE Healthcare Protein A affinity media.

MabSelect

MabSelect SuRe™ - alkali-stabilized protein A ligand

MabSelect Xtra™ - improved efficiency


Other Protein A affinity media lend excellent support, and Protein G provides useful complementary binding specificities.

IgSelect - High purity in one step for human IgG

KappaSelect - Fab purification

rProtein A Sepharose™ 4 Fast Flow

rmp Protein A Sepharose Fast Flow

nProtein A Sepharose 4 Fast Flow

Protein G Sepharose 4 Fast Flow